Super Mario 3. The whole thing was epic.
Super Mario Bros. 3 & The Wizard, TMNT, Ninja Gaiden, and Superman 64 were all hilarious.
Lester the Unlikely.
They're all so funny, but I'd have to say a few of my favorites are Action 52 for the NES, Bugs Bunny's Birthday Blowout, Lester the Unlikely, and his most dreaded game, Dr. Jekyll and Mr. Hyde.
Bugs Bunny's Birthday Blowout, Action 52, and Plumbers Don't Wear Ties. All too funny!