Since this has only actually happened twice, there is only two options on the poll.
Misty and May met in AG, in three separate occasions, (Togepi 2-parter, Pallet eps after Hoenn, Mastermind special). May and Dawn met in DP during the Wallace Cup episodes. Which was altogether 4 eps. Which two female protagonists had better character interaction or chemistry together?
I would have liked to include a Dawn/Misty option on the poll, but of course they never met in the anime, and I can't exactly include Dawn's reaction to the Misty lure, since that wasn't Misty herself. At this point I doubt Dawn and Misty will ever meet, so I guess we'll never know. Misty never appeared in DP, and now with Dawn off the show, that boat has sailed.
And again I can't include Iris options yet, because so far no main girls have returned to meet her.
So between Misty/May and May/Dawn, based on the episodes, which two characters had better interactions and chemistry together?