The first thing you notice is that the grunts have absolutely no idea what the goals of Team Galaxy are but will do everything to stop you stopping them.
The next thing, of course, is the megalomania of the leader. The goal of Team Galaxy is thus: to destroy the known universe, and create it anew with himself as a god.
The goals of the antagonists get more and more surreal... what's next? I'm not sure you can really top that level of insanity.
Finally, I would like to comment on the fact that some of the grunts are given... L.30+ Wurmple, Cascoon/Silcoon and Dustox/Beautifly. How utterly ridiculous. (On the other hand, the skunks and the cats are annoying, the fat one especially - it seems to have a huge amount of HP.)