Whether it's a remake or a second chapter, I would like to see Hoenn in 3D. Considering the events of RSE are years before Black and White, it would be a new strategy to have one generation cover two timeframes.
It's hard to say. I picture a remake more than a sequel. It'd be interesting to see how it plays out. I'm sure that early next year we'll be hearing something about this or the inevitable third version for Black and White.