I may lose some of the respect I have for the franchise (or at least stop playing new games) if...
...they create more and more fanservice-y characters like Skyla, Elesa or even Marlon.
...they put romance and pointless aspects like this in the future games.
...they change everything in the next games to ugly 3D environments like in some spin-off games for consoles.
...they start selling new Pokémon via DLC. I would probably keep playing the games, but I would lose the respect I always had for Game Freak.
Yep, that is all.
Ops, wait, there is something else: