Well, now I have a guess.
After Team Plasma being written out, and maybe Ghetsis and Achroma being arrested/somehow managed to escape, Looker receives a call from the International Police regardind Team Rocket and their 'experiments' with Pokémon (yeah, that's where Mewtwo enters in), as well as Team Plasma's. Knowing they're still looking to conquer Unova, Looker, alongside with Ash and cia, start to investigate possible locals that they might appear, then comes the Genesect Film and maybe a final assault into Team Rocket's Headquarters in Kanto.
My mind may have gone too far away, but that's it :~
Some Iris/Cilan episodes (Iris beats Drayden. Cilan beats Burgundy, Iris leaves, Cilan goes on to Gen 6)
Another 4-episode-worse-than-junior-cup-tournament-arc-in-which-Burgundy-is-a-loser-Georgia-just-wins-against-COTDs-and-loses-against-a-normal-rival-Trip-beats-the-crap-out-of-everyone-and-Iris-has-obedience-problems-with-her-Pokemon thing. Probably Ash wins it
One or Two Pallet town episodes, just before season 6 (or even better, no Pallet Town at all, just right off to France!)
I'm gonna go out on a limb, and say that Black White Season 2: World Tournament is gonna happen, and not just in Unova. We don't know where the NYC city is based, and I could easily see them doing something crazy, like having a tournament in each region, with the tournament in Johto taking place somewhere in July. The reason for this is cause the city is really Mewtwo's City at the end of Mewtwo's Return. Kanto would be in September-October, with someone important brining out a gen 6 Pokemon to give incentive to ash to go to Pokefrance, and boom you have your season.
Burgundy, Georgia, Bianca, and Stephan were completely screwed over in their final appearances.
I'd say give one more proper tournament to help them prove themselves. Burgundy should tie or beat Cilan, Georgia should beat Iris to show her she still has a long way to go. Bianca should beat Stephan, but only after Stephan beats....Virgil's new Eevee evolution? Nah, they'll probably have Ash beat him for that.
Not that I expect Virgil back, but to not make his appearance on this show so pointless Ash should defeat him with Generation 6's new Eevee evo. Sylveon I think it is?
With the gap of episodes left until Generation 6, it's almost hard to believe that there WON'T be another tournament again. But with Best Wishes rate of giving some crappy tournaments I just hope it is not only well written but also not rushed.
I can dig a 6 episode tournament with 3 vs 3. It will give rivals proper closure, Iris and Cilan some proper closure, and possible give Ash some more cred and give us something to look forward to for Generation 6. I just pray there is no cheapness.
I also don't like the idea the Team Rocket Organization in Unova again, but if the TRio were there and apparently hijacked TP's intels, so that means they hadn't given up yet.
Wrapping up Iris vs Georgia and Cilan vs Cabernet rivalry
Ash goes back to Pallet town
Meets Gary and hears of a new region
I don't know what they're going to do. All I know is that there isn't anything left from the games that deserves featuring, unless they really really want to bring Benga in here, and even though they handled Opelucid with neutrality, White Forest/Black City cannot be compromised, unless they somehow BOTH exist in roughly the same location. In any case, where would Benga's Tower of Doom be? I really don't want another tournament. I really really don't. The only thing that I find to be plausible is Georgia getting another chance, but it would serve little purpose. We already know Dragonite can beat her, regardless of how skilled Iris is, which she has improved with Dragonite since then. If you want Georgia to show humility, you know she isn't going to do that too much. It would be redundant to me. Burgundy is just an all out failure. She doesn't even deserve to fight Cilan, ever. However, if he is going to go out, I want to see closure for him. I don't know how to do it because it doesn't seem Cilan has progressed much at all, other than perhaps realizing pokemon is more than what is on the surface. Expecting any of this, however, is almost idiocy considering how BW has treated us. I may have even jumped the gun there, but I really don't think we need to repeat the mistake of Brock and have this go on for more than one gen. It's almost a forgone conclusion they will off Iris, they said so themselves they do it for fanservice. I am done with debating over Ash. I no longer care what happens to him, I just want some quality before I explode.
I'm not quite sure what they'll do exactly. There isn't much left in the games to adapt and I don't know if there would be enough time for Ash to travel through Kanto for a bit, or why Iris and Cilan would come along with him to a faraway region. I could see them creating a new area in Unova, or at least near it, for Ash to explore for awhile before the X/Y series starts.